Are medical laboratory and hospital staff exposed to gaseous inhalation not at health risks.
Udeme KE1, Enwere T1, Oti ME1, Obuna AJ2, Uro-Chukwu HC2,3*
1Medical laboratory Department, National Obstetrics Fistula Centre Abakaliki, Ebonyi State, Nigeria.
2Department of Medical Services, National Obstetrics Fistula Centre, Abakaliki, Ebonyi State, Nigeria.
3Department of Community Medicine, Faculty of Clinical Medicine, Ebonyi State University, Abakaliki, Nigeria.
*Correspondence: Dr. Uro-Chukwu, Henry Chukwuemeka; +234-8035854750; firstname.lastname@example.org; email@example.com
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Toxic exposures are most likely to occur via inhalation, direct contact with the skin or eyes and ingestion, though inhalation with associated fatalities is the most commonly reported. Gases and vapours are the most frequently inhaled substances; nevertheless, liquids and solids can also be inhaled in the form of finely divided mists, aerosols, or dusts. Inhaled substances may cause injury in pulmonary epithelium, reproductive system and other body organs leading to severe disease from simple symptoms. Both hospital and laboratory personnel are affected directly or indirectly. The sources of these toxic inhalants range from environmental contamination to poor professional procedures. International Agency for Research on Cancer in their classification listed that some of these hospital-based inhalants are implicated in cancer pathogenicity, thus need for conscious awareness. The aim of this commentary is to highlight gaseous inhalation hazards associated with medical laboratory and hospital staff, with a view to ensuring preventive procedure that will improve staff safety and health status.
Key words: Medical workers, Inhalation of gases, Health risks.
Cite this article: Udeme KE, Enwere T, Oti ME, Obuna AJ, Uro-Chukwu HC. Are medical laboratory and hospital staff exposed to gaseous inhalation not at health risks? A commentary. Yen Med J. 2020;2(2):1–4.
- Borayek GE, Abou El-Magd SA, El-Gohary SS, El-Naggar AM, Hammouda MA. Occupational Genotoxic Effects Among A Group of Nurses Exposed to Anesthetic Gases in Operating Rooms At Zagazig University Hospitals. Egypt. J. Occup. Med. 2018;42(1):105-122.
- Kawanishi M, Matsuda T, Yagi T. Genotoxicity of formaldehyde: molecular basis of DNA damage and mutation. Frontiers in Environmental Sci. 2014;2:36 – 39. https://www.frontiersin.org/articles/10.3389/fenvs.2014.00036/full. Accessed February 25, 2020.
- Nielsen GD, Larsen, ST, Wolkoff P. Re-evaluation of the WHO formaldehyde indoor air quality guideline for cancer risk assessment. Arch Toxicol. 2010;91(1):35-61.
- Vulimiri SV, Pratt MM, Kulkarni S, Beedanagari S, Mahadevan B. Reproductive and Developmental toxicity of solvents and gases, In: Gupta RC, ed. Reproductive and Developmental Toxicology. 2nd Amsterdam, NH: Academic Press; 2017: 379-396.
- Metin G, Metin A. Acute Inhalation Injury. Eurasian J Med. 2010;42(1):28–3 https://www.csun.edu/sites/default/files/VOC%20MIXTURES-%20TOXICITY%20AND%20ADVERSE%20HEALTH%20EFFECTS%20ASSOCIATED%20WITH%20 5.
- Robins M, Nava F, Anasco H. Voc mixtures: toxicity and adverse health effects associated with coexposure to xylene and formaldehyde. In: Department of Environmental and Occupational Health, California State University, Northridge (database online). Northridge, CA: CSUN. https://www.csun.edu/sites/default/files/VOC%20MIXTURES-%20TOXICITY%20AND%20ADVERSE%20HEALTH%20EFFECTS%20ASSOCIATED%20WITH%20COEXPOSURE%20TO%20XYLENE%20AND%20FORMALDEHYDE.pdf. Accessed February 25, 2020.
- Kwon SC, Kim I, Song J, Park J. Does formaldehyde have a causal association with nasopharyngeal cancer and leukaemia? Ann Occup Environ Med. 2018;30:5-9. doi:10.1186/s40557-018-0218-z.
- Rajan TS, Malathi N. Health hazards of xylene: a literature review. J Clin Diagn Res. 2014;8(2):271–274.
- Occupational hygiene training association (OHTA). STUDENT MANUAL Basic Principles in Occupational Hygiene. OH learning.com http://www.ohlearning.com/Files/Student/KA02%20v3-0%2022Aug17%20Student%20Manual.pdf. Accessed February 25, 2020.
- Borm PJ, Schins RP, Albrecht C. Inhaled particles and lung cancer, part B: paradigms and risk assessment. Int J Cancer. 2004;110(1):3–14. doi:10.1002/ijc.20064
- Public Health England. Formaldehyde: health effects, incident management and toxicology. GOV.UK. https://www.gov.uk/government/publications/formaldehyde-properties-incident-management-and-toxicology. Published July 1, 2014. Updated November 16, 2017. Accessed February 25, 2020.
- Cogliano VJ, Baan R, Straif K, Grosse Y, Lauby-Secretan B, El Ghissassi F, et al. Preventable exposures associated with human cancers. J Natl Cancer Inst. 2011;103:1827–1839.
- International Agency for Research on Cancer. Evidence for Carcinogenicity 2012. http://monographs.iarc.fr/ENG/Classification/index.php. Accessed October 10, 2019.
- Swenberg JA, Moeller BC, Lu K, Rager JE, Fry RC, Starr TB. Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment. Toxicol Pathol. 2013;41(2):181–189.
- Sandvik A, Klingen TA. Langård S. Sinonasal adenoid cystic carcinoma following formaldehyde exposure in the operating theatre. J Occup Med Toxicol. 2014;9:43 – 51. doi:10.1186/s12995-014-0043-4.2019
- Sivasankari NP, Sundarapandian S, Sakthivel E Micronucleus assay in formalin exposed individuals. Indian J Clin Anat Physiol. 2018;5(1);81-84.
- Williams GW, Gumbert S, Pivalizza EG, Syed TA, Burnett, T, Mancillas OL, et al. Evaluation and control of waste anesthetic gas in the postanesthesia care unit within patient and caregiver breathing zones. Proc (Bayl Univ Med Cent). 2018;32(1):43-49.
- Kampan S. Air quality and employee hygiene-related behavior in a post anesthesia care unit in Thailand. Asian Pac Island Nurs J. 2019;4:11-19.
- Siha MS, Farahat SA, Rashed LA, Helmy NM. Study of some health hazards among operating theater personnel due to exposure to anesthetic gases (II). Egypt. J. Occup. Med. 2019;43:313-329.
- Nagella AB, Ravishankar M, Hemanth Kumar VR. Anaesthesia practice and reproductive outcomes: Facts unveiled. Indian J Anaesth. 2015;59(11):706–714. doi:10.4103/0019-5049.170028
- Kandyala R, Raghavenda SP, Rajasekharam ST. Xylene an over view of it’s hazard and preventive measure. Oral Maxillofac. Pathol. 2010;14(1):1-5.
- Agency for Toxic Substances & Disease Registry. Medical management guidelines
for xylene. ASTDR https://www.atsdr.cdc.gov/MMG/MMG.asp?id=291&tid=53. Accessed October 11, 2019.
- Wen-His C, Hui-Min W. Assessing organic chemical emission and works risk of exposure in a medical examination Centre using solid phase microextraction device. Aerosol Air Qual Res. 2019;19:865-870.
- Kuranchie FA, Angnunavuri PN, Attiogbe F, Nerquaye-Tetteh, EN. Occupational exposure of benzene, toluene, ethylbenzene and xylene (BTEX) to pump attendants in Ghana: Implications for policy guidance. Cogent Sci. 2019;5:1-9. https://www.tandfonline.com/doi/full/10.1080/23311843.2019.1603418. Accessed February 25, 2020.