Prevalence of macrosomia and associated complications as seen in a neonatal unit of a Tertiary Hospital in South Eastern Nigeria

Daniyan OW1*, Ezeanosike OB1,2, Obu DC1, Onwe OE1,2, Asiegbu UV1,2, Joe-Akunne CI1
1Department of Paediatrics, Alex Ekwueme Federal University Teaching Hospital, Abakaliki Ebonyi State, Nigeria.
2Department of Paediatrics, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria
*Correspondence:  Dr. Olapeju Wunmi Daniyan; daniyanolapeju@gmail.com

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Abstract

Background: Macrosomia contributes to neonatal morbidity and mortality.  Macrosomic birth is associated with an increased need for Caesarean section or instrumental deliveries and neonatal resuscitation.
Objective: This study aims to determine the prevalence of macrosomia and associated complications among neonates admitted into a newborn unit in South Eastern Nigeria.
Materials and Methods:  It was a 3-year retrospective descriptive study, carried out at the Newborn Special Care Baby Unit of Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria, between 1st May, 2016 and 30th April, 2019. Admission files of all babies with birth weight ≥ 4000g were retrieved for information including birth weight, length, head circumference, mode of delivery and duration of hospital stay. Maternal parity, maternal age, gestational age, history of previous delivery of a macrosomic baby and complications observed during pregnancy were also recorded in a proforma. Data obtained were analysed using SPSS version 22.
Results:  A total of 1133 babies were admitted during the study period, of these, 74 babies were macrosomic giving a prevalence of 6.5%. Most (66.2%) of the babies were males and fifteen (20.3%) of the mothers had a history of diabetes mellitus. The commonest complication was birth trauma.
Conclusion: Macrosomia contributes to neonatal morbidity, therefore adequate monitoring during antenatal care and during delivery of both mother and baby should be done to reduce neonatal complications.

Keywords:  Newborn, Macrosomia, Birth weight, Prevalence, Complications

Cite this article: Daniyan OW, Ezeanosike OB, Obu DC, Onwe OE, Asiegbu UV, Joe-Akunne CI. Prevalence of macrosomia and associated complications as seen in a neonatal unit of a Tertiary Hospital in South Eastern Nigeria. Yen Med J. 2021;3(3):187–191.

REFERENCES   

  1. Kamana KC, Shakya S, Zhang H. Gestational diabetes mellitus and macrosomia: a literature review. Ann Nutr Metab. 2015;66:14-20. doi: 10.1159/000371628.
  2. Usta A, Usta CS, Yildiz A, Ozcaglayan R,Dalkiran ES, Savkli A et al. Frequency of fetal macrosomia and the associated risk factors in pregnancies without gestational diabetes.  Pan Afr Med J. 2017;26:62. doi: 10.11604/pamj.2017.26.62.11440.
  3. Adegbola O, Habeebu-Adeyemi FM. Fetal Macrosomia at a Tertiary Care Centre in Lagos, Nigeria. Nig Q J Hosp Med. 2015;25:90-94.
  4. Mai AH, Abbassia D. The Prevalence of Fetal Macrosomia at the Specialized Hospital of Gynecology and Obstetrics of Sidi Bel Abbes (West Of Algeria ).  J Nutr Food Sci. 2014;4:3. doi: 10.4127/2155-9600.1000272.
  5. Tela RG,Bezabih AM,Adhanu AK, Tekola KB. Fetal macrosomia and its associated factors among singleton live-births in private clinics in Mekelle city, Tigray, EthiopiBMC Pregnancy Childbirth. 2019;19:219. doi: 10.1186/s12884-019-2379-2383.
  6. Davis R, Woelk G, Mueller BA and Daling J. The Role of Previous Birth weight on Risk for Macrosomia in a Subsequent Birth. 1995;6:607-611.
  7. Nkwabong E, Nzalli Tangho GR. Risk factors for macrosomia. J Obstet Gynaecol India. 2015;65:226-229. doi: 10.1007/s13224-014-0586-4.
  8. Nkwabong E. Maternal and neonatal complications of macrosomia. Trop Doct. 2014;44:201-204. doi: 10.1177/0049475514539479.
  9. Alsammani MA, Ahmed SR. Fetal and maternal outcomes in pregnancies complicated with fetal macrosomia. N Am J Med Sci. 2012;4:283-286. doi: 10.4103/1947-2714.97212.
  10. Yu ZB, Han SP, Zhu GZ, Zhu C, Wang XJ, Cao XG, et al. Birth weight and subsequent risk of obesity: a systematic review and meta-analysis. Obes Rev. 2011;12:525-542. doi: 10.1111/j.1467-789x.2011.00867.x.
  11. Boulet SL, Alexander Gr, Salihu HM, Pass M. Macrosomic births in the United States: determinants, outcomes and proposed grades of risk. Am J Obstet Gynecol. 2003;188(5):1372-1378. doi: 10.1067/mob.2003.302.
  12. Ezegwui HU, Ikeako LC, Egbuji C. Fetal macrosomia: Obstetric outcome of 311 cases in UNTH, Enugu, Nigeria. Niger J Clin Pract. 2011;14:322-326. doi: 10.4103/1119-3077.86777.
  13. Olokor OE,  Onakewhor JU, Aderoba Determinants and outcome of fetal macrosomia in a Nigerian tertiary hospital. Niger Med J. 2015;56:411-415. doi: 10.4103/0300-1652.171622.
  14. Onyearugha CN, Ugboma HAA. Macrosomia: Prevalence and predisposing factors as seen at a university teaching hospital, South-South Nigeria. J Med Investig Pract. 2014;9:12-15.
  15. Adugna DG, Enyew EF, Jemberie MT. Prevalence and associated factors of macrosomia among newborns delivered in university of Gondar comprehensive specialized hospital, Gondar, Ethiopia: an institution-based cross-sectional study. Pediatric Health Med Ther. 2020;11:495-593.
  16. Martin JA, Hamilton BE, Osterman MJK, Driscoll AK. Births: Final Data for 2018. Natl Vital Stat Rep. 2019;68(13):1-47.
  17. Akindele RN, Audu LI, Mokuolu OA. Macrosomic Births in Abuja: A Case–Control Study of Predisposing Factors and Early Neonatal Outcome. Niger J Clin Pract. 2017;20:320-327.
  18. Said AS, Manji KP. Risk factors and outcomes of fetal macrosomia in a tertiary centre in Tanzania: a case control study. BMC Pregnancy Childbirth. 2016;16:243. doi: 10.1186/s12884-016-1044-3.
  19. Turkmen S, Johansson S, Dahmoun M. Foetal Macrosomia and Foetal-Maternal Outcomes at Birth. J Pregnancy. 2018;2018:4790136.
  20. Peleg D, Warsof S, Wolf MF, Perlitz Y, Shachar IB. The effect of fetal weight estimation on cesarean section rates of macrosomic babies. Am J Obstet Gynecol. Suppl 2014; Poster Session IV-Operative Obstetrics, Clinical Obstetrics, Intrapartum, Medical-Surgical. Available from: https://www.ajog.org/article/S0002-9378(13)01774-2/pdf. Accessed June 18, 2021.
  21. Cheng Y, Sparks T, Laros R Jr, Nicholson J, Caughey A. Impending macrosomia: Will induction of labour modify the risk of caesarean delivery? 2012;119:402-409. doi: 10.1111/j.1471-0528.2011.03248.x.
  22. Tolosa JN, Calhoun DA. Maternal and neonatal demographics of macrosomic infants admitted to the neonatal intensive care unit. J Perinatol. 2017;37:1292-1296.
  23. Onankpa BO, Nauzo AM. Prevalence and outcome of macrosomic babies admitted to the special care baby unit of a teaching hospital. Res J Health Sci. 2015;3:31-37.
  24. Scotland NE, Caughey AB, Breed EM, Escobar GJ. Risk factors and obstetric complications associated with macrosomia. Int J Gynaecol Obstet. 2004;87:220-226. doi:10.1016/j.ijgo.2004.08.010.
  25. Mardani M, Khalkhalirad A,  Rossta S, Rezapour P. Evaluation of the Prevalence of  Macrosomia and the Maternal Risk Factors. Iran J Neonatol. 2014;5:5-9. doi: 10.22038/ijn.2014.4141.
  26. Gu S, An X, Fang L, Zhang X, Zhang C, Wang J et al. Risk factors and long-term health consequences of macrosomia: a prospective study in Jiangsu Province. China J Biomed Res. 2012;26:235-240. doi: 10.7555/JBR.26.20120037.
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