Spirometric parameters and the relationship between peak expiratory flow (PEF) measured with peak flow meters and forced expiratory volume in one second (fev1) among a sample of asthmatics in South-West Nigeria

Jumbo J*, Ambakederemo TE, Ikuabe PO
Department of Internal Medicine, Niger Delta University, Bayelsa State, Nigeria.
*Correspondence: Dr. Jumbo, Johnbull; johnbulljumbo@gmail.com

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Background: Although forced expiratory volume in one second (FEV1) which is measured in spirometry is the gold standard for functional airway obstruction measurement, it is not available to most clinicians managing asthmatic patients in Nigeria. Peak expiratory flow (PEF) is useful in assessing bronchial airway calibre and it is used frequently in monitoring response to treatment of asthmatic patients.
Objective: To investigate the spirometric findings and the relationship between PEF measured with peak flow meter and FEV1 among asthmatic patients.
Materials and Methods: A cross-sectional descriptive study of asthmatic patients seen at the medical outpatient clinics of Obafemi Awolowo University Teaching Hospitals Complex, Ile-lfe and the OAUTHC, Wesley Guild Hospital, Ilesa. A proforma was used to record information on socio-demographic data, clinical features and spirometric parameters of each patient. Spirometry was carried out according to the American Thoracic Society (ATS) guidelines and PEF, FEV1, FVC and FEV1/FVC were measured.
Results: The mean pre-bronchodilator FEV1 was 1.97 ± 0.87 (L), and the post bronchodilator FEV1 was 2.32 ± 0.95 (L). The mean pre-bronchodilator PEF was 286 ± 107(L/ Min) and the post bronchodilator PEF was 348 ± 114(L/Min). Males had higher values when compared with females in FEV1 and FVC and the differences were statistically significant. There was a significant correlation between PEFR and FEV1.
Conclusion: There was statistically significant correlation between PEF and FEV1 among the patients with asthma studied.

Keywords: Peak expiratory flow (PEF), Forced expiratory volume in one second (FEV1), Asthmatics, South West Nigeria.

Cite this article: Jumbo J, Ambakederemo TE, Ikuabe PO. Spirometric parameters and the relationship between peak expiratory flow (PEF) measured with peak flow meters and forced expiratory volume in one second (fev1) among a sample of asthmatics in South-West Nigeria. Yen Med J. 2022;4(3):62–66.


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