Spirometric parameters and the relationship between peak expiratory flow (PEF) measured with peak flow meters and forced expiratory volume in one second (fev1) among a sample of asthmatics in South-West Nigeria

Jumbo J*, Ambakederemo TE, Ikuabe PO
Department of Internal Medicine, Niger Delta University, Bayelsa State, Nigeria.
*Correspondence: Dr. Jumbo, Johnbull; johnbulljumbo@gmail.com

Download full article in pdf format

Abstract

Background: Although forced expiratory volume in one second (FEV1) which is measured in spirometry is the gold standard for functional airway obstruction measurement, it is not available to most clinicians managing asthmatic patients in Nigeria. Peak expiratory flow (PEF) is useful in assessing bronchial airway calibre and it is used frequently in monitoring response to treatment of asthmatic patients.
Objective: To investigate the spirometric findings and the relationship between PEF measured with peak flow meter and FEV1 among asthmatic patients.
Materials and Methods: A cross-sectional descriptive study of asthmatic patients seen at the medical outpatient clinics of Obafemi Awolowo University Teaching Hospitals Complex, Ile-lfe and the OAUTHC, Wesley Guild Hospital, Ilesa. A proforma was used to record information on socio-demographic data, clinical features and spirometric parameters of each patient. Spirometry was carried out according to the American Thoracic Society (ATS) guidelines and PEF, FEV1, FVC and FEV1/FVC were measured.
Results: The mean pre-bronchodilator FEV1 was 1.97 ± 0.87 (L), and the post bronchodilator FEV1 was 2.32 ± 0.95 (L). The mean pre-bronchodilator PEF was 286 ± 107(L/ Min) and the post bronchodilator PEF was 348 ± 114(L/Min). Males had higher values when compared with females in FEV1 and FVC and the differences were statistically significant. There was a significant correlation between PEFR and FEV1.
Conclusion: There was statistically significant correlation between PEF and FEV1 among the patients with asthma studied.

Keywords: Peak expiratory flow (PEF), Forced expiratory volume in one second (FEV1), Asthmatics, South West Nigeria.

Cite this article: Jumbo J, Ambakederemo TE, Ikuabe PO. Spirometric parameters and the relationship between peak expiratory flow (PEF) measured with peak flow meters and forced expiratory volume in one second (fev1) among a sample of asthmatics in South-West Nigeria. Yen Med J. 2022;4(3):62–66.

REFERENCES

  1. Gao C, Zhang X, Wang D, Wang Z, Li J, Li Z. Reference values for lung function screening in 10- to 81-year-old, healthy, never-smoking residents of Southeast China. Medicine (Baltimore). 2018;97(34):e11904.
  2. Cen J, Ma H, Chen Z, Weng L, Deng Z. Monitoring peak expiratory flow could predict COPD exacerbations: A prospective observational study. Respir Med. 2019;148:43-48.
  3. Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, et al. International European Respiratory Society/American Thoracic Society guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J; 2014 Feb;43(2):343-373.
  4. Global Initiative for Asthma. 2022 GINA Report, Global Strategy for Asthma Management and Prevention. Available from: https://ginasthma.org/gina-reports. Accessed September 12, 2022.
  5. Asthma: diagnosis, monitoring and chronic asthma management, NICE guideline [NG80]. Available from: https://www.nice.org.uk/guidance/ng80. Published November 29, 2017. Updated March 22, 2021. Accessed September 12, 2022.
  6. Hill B. Measuring peak expiratory flow in adults with asthma. Br J Nurs. 2019;28(14):924-926.
  7. Quirt J, Hildebrand KJ, Mazza J, Noya F, Kim H. Asthma. Allergy Asthma Clin Immunol. 2018;14(Suppl 2):50.
  8. Aalbers R, Vogelmeier C, Kuna P. Achieving asthma control with ICS/LABA: A review of strategies for asthma management and prevention. Respir Med. 2016;111:1-7.
  9. Kaushal A. Evaluation of Peak Expiratory Flow Rate and Forced Expiratory Volume in One Second in Indian Children with Suspected Asthma. Int J Adv Res Dev. 2017;2(6):154-163.
  10. So JY, Lastra AC, Zhao H, Marchetti N, Criner GJ. Daily Peak Expiratory Flow Rate and Disease Instability in Chronic Obstructive Pulmonary Disease. Chronic Obstr Pulm Dis. 2015;3(1):398-405.
  11. Riyadh Farhan Alanazi, Sreekanth Komath, Sami Faleh Almutairi, Hasan Salim Alqarni, Abdullah Fraih Alharbi, et al. Comparison between peak expiratory flow rate (pefr) and forced expiratory volume in first second (fev1) in monitoring the airway status of students studying in college of applied medical sciences, Int J Dev Res. 2018;8;1-9.
  12. Graham BL, Steenbruggen I, Miller MR, et al. Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement. Am J Respir Crit Care Med. 2019;200(8):e70-e88.
  13. Urbankowski T, Przybyłowski T. Methacholine Challenge Testing: Comparison of FEV1 and Airway Resistance Parameters. Respir Care. 2021;66(3):449-459.
  14. Cuttica MJ, Colangelo LA, Dransfield MT, et al. Lung Function in Young Adults and Risk of Cardiovascular Events Over 29 Years: The CARDIA Study. J Am Heart Assoc. 2018;7(24):e010672.
  15. Feng Y, Yu XH, Song YX, et al. Establishment of a predictive equation for pulmonary ventilation function in school-aged children in northeast China: a prospective study. Zhongguo Dang Dai Er Ke Za Zhi. 2021;23(11):1119-1126.
  16. Çautrin D, D’Aquino LC, Gagnon_Q, MaloJL, Cartier A Comparison between peak expiratory flow rates (PEFR) and FEVI in the monitoring of asthmatic subjects at an outpatient clinic. Chest. 1994;106(5):1419-1426.
  17. Iseon S Choi, Youngil I Koh, Ho Lim. Peak expiratory flow rate underestimate Severity of Airflow obstruction in Acute Asthma. Korean J Intern Med. 2002;7(3):174-179.
  18. Thiadens HA, De Bock GH, Van Houwelingen JC, Dekker FW, DeWaal M W, Springer MP, Postma D.S. Can peak expiratory flow measurements reliably identify the presence of airway obstruction and bronchodilator response as assessed by FEVI in primary care patients presenting with a persistent cough? Thorax. 1999;54: 1055-1060.
Scroll to Top
× Chat